An Organ-On-Chip (OOC) is a multi-channel 3-D microfluidic cell culture chip that simulates the activities, mechanics and physiological response of entire organs and organ systems, a type of artificial organ. It constitutes the subject matter of significant biomedical engineering research, more precisely in bio-MEMS. The convergence of labs-on-chips (LOCs) and cell biology has permitted the study of human physiology in an organ-specific context, introducing a novel model of in vitro multicellular human organisms. One day, they will perhaps abolish the need for animals in drug development and toxin testing. Organ-On-Chip technology not only incorporates multiple cell types but also involves engineering aspects, such as the guided spatial confinement of cells or the incorporation of sensors and microfluidic channels.

The primary focus of Organ-On-Chip technology is the re-creation of three key aspects of human physiology: the multicellular vascular or epithelial interfaces of organs (for example, blood vessel networks, lung and gut), which function as barriers in tissues; the tissue-level organization of parenchymal cells (for example, liver, heart, skeletal muscle and tumours), which are responsible for the key functional properties of an organ; and the systematic interaction of multiple organs (for example, drug absorption, distribution, metabolism and elimination involving the gut, circulation, liver and kidney).

In addition, the Blood-Brain Barrier is definitely more complex than a simple wall, controlling the passage of most solute that enters or leaves the brain. To address how this molecular sieve affects neural activity, some researchers have simulated the interaction between blood vessels and brain tissue on a series of interconnected "organ chips" when connected through this Blood-Brain Barrier (BBB) model. Endothelial cells, pericytes, astrocytes and neurons alter their gene expression. These technologies will achieve even more rapid development and application.

This report aims to provide a comprehensive presentation of the global market for Organ On Chip study by Market Intellix gives insights concerning the market elements influencing the market, Market scope, Market division, and overlays shadow upon the leading market players featuring the positive cutthroat scene and patterns beating the years.

Global Organ On Chip Market Revenue, 2017-2022, 2023-2028, ($ millions)

Global Organ On Chip Market Sales, 2017-2022, 2023-2028, (K Units)

Global top five Organ On Chip companies in 2021 (%)

The global Organ On Chip market was valued at 58 million in 2021 and is projected to reach US$ 554.4 million by 2028, at a CAGR of 38.2% during the forecast period 2022-2028.

The U.S. Market is Estimated at $ Million in 2021, While China is Forecast to Reach $ Million by 2028.

Brain-on-a-chip Segment to Reach $ Million by 2028, with a % CAGR in next six years.

The global key manufacturers of Organ On Chip include Emulate, TissUse, Hesperos, CN Bio Innovations, Tara Biosystems, Draper Laboratory, Mimetas, Nortis and Micronit Microtechnologies B.V., etc. In 2021, the global top five players have a share approximately % in terms of revenue.

The study provides the Organ On Chip manufacturers, suppliers, distributors and industry experts on this industry, involving the sales, revenue, demand, price change, product type, recent development and plan, industry trends, drivers, challenges, obstacles, and potential risks.

Segmental Outline:

Global Organ On Chip Market, by Type, 2017-2022, 2023-2028 ($ Millions) & (K Units)

Global Organ On Chip Market Segment Percentages, by Type, 2021 (%)

Brain-on-a-chip

Liver-on-a-chip

Kidney-on-a-chip

Lung-on-a-chip

Heart-on-a-chip

Intestine-on-a-chip

Vessel-on-a-chip

Other Organs

Global Organ On Chip Market, by End User, 2017-2022, 2023-2028 ($ Millions) & (K Units)

Global Organ On Chip Market Segment Percentages, by End User, 2021 (%)

Pharmaceutical & Biotechnology Companies

Academic & Research Institutes

Cosmetics Industry

Others

Global Organ On Chip Market, By Region and Country, 2017-2022, 2023-2028 ($ Millions) & (K Units)

Global Organ On Chip Market Segment Percentages, By Region and Country, 2021 (%)

North America

US

Canada

Mexico

Europe

Germany

France

U.K.

Italy

Russia

Nordic Countries

Benelux

Rest of Europe

Asia

China

Japan

South Korea

Southeast Asia

India

Rest of Asia

South America

Brazil

Argentina

Rest of South America

Middle East & Africa

Turkey

Israel

Saudi Arabia

UAE

Rest of Middle East & Africa

Competitor Analysis

The report also provides analysis of leading market participants including:

Key companies Organ On Chip revenues in global market, 2017-2022 (Estimated), ($ millions)

Key companies Organ On Chip revenues share in global market, 2021 (%)

Key companies Organ On Chip sales in global market, 2017-2022 (Estimated), (K Units)

Key companies Organ On Chip sales share in global market, 2021 (%)

Further, the report presents profiles of competitors in the market, key players include:

Emulate

TissUse

Hesperos

CN Bio Innovations

Tara Biosystems

Draper Laboratory

Mimetas

Nortis

Micronit Microtechnologies B.V.

Kirkstall

Cherry Biotech SAS

Else Kooi Laboratory

Beijing Daxiang Biotech Co., Ltd

This Report Addresses:

– Market Intelligence enables effective decision-making

– Market estimates and forecasts from 2022 to 2028

– Growth opportunities and trend analysis

– Segment and regional revenue forecast for market evaluation

– Competitive strategy and analysis of market segments

– List of product innovations to stay on top.

– The impact of COVID-19 and how to survive in these fast-growing markets.

1 Introduction to Research & Analysis Reports

1.1 Organ On Chip Market Definition

1.2 Market Segments

1.2.1 Market by Type

1.2.2 Market by End User

1.3 Global Organ On Chip Market Overview

1.4 Features & Benefits of This Report

1.5 Methodology & Sources of Information

1.5.1 Research Methodology

1.5.2 Research Process

1.5.3 Base Year

1.5.4 Report Assumptions & Caveats

2 Global Organ On Chip Overall Market Size

2.1 Global Organ On Chip Market Size: 2021 VS 2028

2.2 Global Organ On Chip Revenue, Prospects & Forecasts: 2017-2028

2.3 Global Organ On Chip Sales: 2017-2028

3 Company Landscape

3.1 Top Organ On Chip Players in Global Market

3.2 Top Global Organ On Chip Companies Ranked by Revenue

3.3 Global Organ On Chip Revenue by Companies

3.4 Global Organ On Chip Sales by Companies

3.5 Global Organ On Chip Price by Manufacturer (2017-2022)

3.6 Top 3 and Top 5 Organ On Chip Companies in Global Market, by Revenue in 2021

3.7 Global Manufacturers Organ On Chip Product Type

3.8 Tier 1, Tier 2 and Tier 3 Organ On Chip Players in Global Market

3.8.1 List of Global Tier 1 Organ On Chip Companies

3.8.2 List of Global Tier 2 and Tier 3 Organ On Chip Companies

4 Sights by Product

4.1 Overview

4.1.1 By Type - Global Organ On Chip Market Size Markets, 2021 & 2028

4.1.2 Brain-on-a-chip

4.1.3 Liver-on-a-chip

4.1.4 Kidney-on-a-chip

4.1.5 Lung-on-a-chip

4.1.6 Heart-on-a-chip

4.1.7 Intestine-on-a-chip

4.1.8 Vessel-on-a-chip

4.1.9 Other Organs

4.2 By Type - Global Organ On Chip Revenue & Forecasts

4.2.1 By Type - Global Organ On Chip Revenue, 2017-2022

4.2.2 By Type - Global Organ On Chip Revenue, 2023-2028

4.2.3 By Type - Global Organ On Chip Revenue Market Share, 2017-2028

4.3 By Type - Global Organ On Chip Sales & Forecasts

4.3.1 By Type - Global Organ On Chip Sales, 2017-2022

4.3.2 By Type - Global Organ On Chip Sales, 2023-2028

4.3.3 By Type - Global Organ On Chip Sales Market Share, 2017-2028

4.4 By Type - Global Organ On Chip Price (Manufacturers Selling Prices), 2017-2028

5 Sights By End User

5.1 Overview

5.1.1 By End User - Global Organ On Chip Market Size, 2021 & 2028

5.1.2 Pharmaceutical & Biotechnology Companies

5.1.3 Academic & Research Institutes

5.1.4 Cosmetics Industry

5.1.5 Others

5.2 By End User - Global Organ On Chip Revenue & Forecasts

5.2.1 By End User - Global Organ On Chip Revenue, 2017-2022

5.2.2 By End User - Global Organ On Chip Revenue, 2023-2028

5.2.3 By End User - Global Organ On Chip Revenue Market Share, 2017-2028

5.3 By End User - Global Organ On Chip Sales & Forecasts

5.3.1 By End User - Global Organ On Chip Sales, 2017-2022

5.3.2 By End User - Global Organ On Chip Sales, 2023-2028

5.3.3 By End User - Global Organ On Chip Sales Market Share, 2017-2028

5.4 By End User - Global Organ On Chip Price (Manufacturers Selling Prices), 2017-2028

6 Sights by Region

6.1 By Region - Global Organ On Chip Market Size, 2021 & 2028

6.2 By Region - Global Organ On Chip Revenue & Forecasts

6.2.1 By Region - Global Organ On Chip Revenue, 2017-2022

6.2.2 By Region - Global Organ On Chip Revenue, 2023-2028

6.2.3 By Region - Global Organ On Chip Revenue Market Share, 2017-2028

6.3 By Region - Global Organ On Chip Sales & Forecasts

6.3.1 By Region - Global Organ On Chip Sales, 2017-2022

6.3.2 By Region - Global Organ On Chip Sales, 2023-2028

6.3.3 By Region - Global Organ On Chip Sales Market Share, 2017-2028

6.4 North America

6.4.1 By Country - North America Organ On Chip Revenue, 2017-2028

6.4.2 By Country - North America Organ On Chip Sales, 2017-2028

6.4.3 US Organ On Chip Market Size, 2017-2028

6.4.4 Canada Organ On Chip Market Size, 2017-2028

6.4.5 Mexico Organ On Chip Market Size, 2017-2028

6.5 Europe

6.5.1 By Country - Europe Organ On Chip Revenue, 2017-2028

6.5.2 By Country - Europe Organ On Chip Sales, 2017-2028

6.5.3 Germany Organ On Chip Market Size, 2017-2028

6.5.4 France Organ On Chip Market Size, 2017-2028

6.5.5 U.K. Organ On Chip Market Size, 2017-2028

6.5.6 Italy Organ On Chip Market Size, 2017-2028

6.5.7 Russia Organ On Chip Market Size, 2017-2028

6.5.8 Nordic Countries Organ On Chip Market Size, 2017-2028

6.5.9 Benelux Organ On Chip Market Size, 2017-2028

6.6 Asia

6.6.1 By Region - Asia Organ On Chip Revenue, 2017-2028

6.6.2 By Region - Asia Organ On Chip Sales, 2017-2028

6.6.3 China Organ On Chip Market Size, 2017-2028

6.6.4 Japan Organ On Chip Market Size, 2017-2028

6.6.5 South Korea Organ On Chip Market Size, 2017-2028

6.6.6 Southeast Asia Organ On Chip Market Size, 2017-2028

6.6.7 India Organ On Chip Market Size, 2017-2028

6.7 South America

6.7.1 By Country - South America Organ On Chip Revenue, 2017-2028

6.7.2 By Country - South America Organ On Chip Sales, 2017-2028

6.7.3 Brazil Organ On Chip Market Size, 2017-2028

6.7.4 Argentina Organ On Chip Market Size, 2017-2028

6.8 Middle East & Africa

6.8.1 By Country - Middle East & Africa Organ On Chip Revenue, 2017-2028

6.8.2 By Country - Middle East & Africa Organ On Chip Sales, 2017-2028

6.8.3 Turkey Organ On Chip Market Size, 2017-2028

6.8.4 Israel Organ On Chip Market Size, 2017-2028

6.8.5 Saudi Arabia Organ On Chip Market Size, 2017-2028

6.8.6 UAE Organ On Chip Market Size, 2017-2028

7 Manufacturers & Brands Profiles

7.1 Emulate

7.1.1 Emulate Corporate Summary

7.1.2 Emulate Business Overview

7.1.3 Emulate Organ On Chip Major Product Offerings

7.1.4 Emulate Organ On Chip Sales and Revenue in Global (2017-2022)

7.1.5 Emulate Key News

7.2 TissUse

7.2.1 TissUse Corporate Summary

7.2.2 TissUse Business Overview

7.2.3 TissUse Organ On Chip Major Product Offerings

7.2.4 TissUse Organ On Chip Sales and Revenue in Global (2017-2022)

7.2.5 TissUse Key News

7.3 Hesperos

7.3.1 Hesperos Corporate Summary

7.3.2 Hesperos Business Overview

7.3.3 Hesperos Organ On Chip Major Product Offerings

7.3.4 Hesperos Organ On Chip Sales and Revenue in Global (2017-2022)

7.3.5 Hesperos Key News

7.4 CN Bio Innovations

7.4.1 CN Bio Innovations Corporate Summary

7.4.2 CN Bio Innovations Business Overview

7.4.3 CN Bio Innovations Organ On Chip Major Product Offerings

7.4.4 CN Bio Innovations Organ On Chip Sales and Revenue in Global (2017-2022)

7.4.5 CN Bio Innovations Key News

7.5 Tara Biosystems

7.5.1 Tara Biosystems Corporate Summary

7.5.2 Tara Biosystems Business Overview

7.5.3 Tara Biosystems Organ On Chip Major Product Offerings

7.5.4 Tara Biosystems Organ On Chip Sales and Revenue in Global (2017-2022)

7.5.5 Tara Biosystems Key News

7.6 Draper Laboratory

7.6.1 Draper Laboratory Corporate Summary

7.6.2 Draper Laboratory Business Overview

7.6.3 Draper Laboratory Organ On Chip Major Product Offerings

7.6.4 Draper Laboratory Organ On Chip Sales and Revenue in Global (2017-2022)

7.6.5 Draper Laboratory Key News

7.7 Mimetas

7.7.1 Mimetas Corporate Summary

7.7.2 Mimetas Business Overview

7.7.3 Mimetas Organ On Chip Major Product Offerings

7.7.4 Mimetas Organ On Chip Sales and Revenue in Global (2017-2022)

7.7.5 Mimetas Key News

7.8 Nortis

7.8.1 Nortis Corporate Summary

7.8.2 Nortis Business Overview

7.8.3 Nortis Organ On Chip Major Product Offerings

7.8.4 Nortis Organ On Chip Sales and Revenue in Global (2017-2022)

7.8.5 Nortis Key News

7.9 Micronit Microtechnologies B.V.

7.9.1 Micronit Microtechnologies B.V. Corporate Summary

7.9.2 Micronit Microtechnologies B.V. Business Overview

7.9.3 Micronit Microtechnologies B.V. Organ On Chip Major Product Offerings

7.9.4 Micronit Microtechnologies B.V. Organ On Chip Sales and Revenue in Global (2017-2022)

7.9.5 Micronit Microtechnologies B.V. Key News

7.10 Kirkstall

7.10.1 Kirkstall Corporate Summary

7.10.2 Kirkstall Business Overview

7.10.3 Kirkstall Organ On Chip Major Product Offerings

7.10.4 Kirkstall Organ On Chip Sales and Revenue in Global (2017-2022)

7.10.5 Kirkstall Key News

7.11 Cherry Biotech SAS

7.11.1 Cherry Biotech SAS Corporate Summary

7.11.2 Cherry Biotech SAS Organ On Chip Business Overview

7.11.3 Cherry Biotech SAS Organ On Chip Major Product Offerings

7.11.4 Cherry Biotech SAS Organ On Chip Sales and Revenue in Global (2017-2022)

7.11.5 Cherry Biotech SAS Key News

7.12 Else Kooi Laboratory

7.12.1 Else Kooi Laboratory Corporate Summary

7.12.2 Else Kooi Laboratory Organ On Chip Business Overview

7.12.3 Else Kooi Laboratory Organ On Chip Major Product Offerings

7.12.4 Else Kooi Laboratory Organ On Chip Sales and Revenue in Global (2017-2022)

7.12.5 Else Kooi Laboratory Key News

7.13 Beijing Daxiang Biotech Co., Ltd

7.13.1 Beijing Daxiang Biotech Co., Ltd Corporate Summary

7.13.2 Beijing Daxiang Biotech Co., Ltd Organ On Chip Business Overview

7.13.3 Beijing Daxiang Biotech Co., Ltd Organ On Chip Major Product Offerings

7.13.4 Beijing Daxiang Biotech Co., Ltd Organ On Chip Sales and Revenue in Global (2017-2022)

7.13.5 Beijing Daxiang Biotech Co., Ltd Key News

8 Global Organ On Chip Production Capacity, Analysis

8.1 Global Organ On Chip Production Capacity, 2017-2028

8.2 Organ On Chip Production Capacity of Key Manufacturers in Global Market

8.3 Global Organ On Chip Production by Region

9 Key Market Trends, Opportunity, Drivers and Restraints

9.1 Market Opportunities & Trends

9.2 Market Drivers

9.3 Market Restraints

10 Organ On Chip Supply Chain Analysis

10.1 Organ On Chip Industry Value Chain

10.2 Organ On Chip Upstream Market

10.3 Organ On Chip Downstream and Clients

10.4 Marketing Channels Analysis

10.4.1 Marketing Channels

10.4.2 Organ On Chip Distributors and Sales Agents in Global

11 Conclusion

12 Appendix

12.1 Note

12.2 Examples of Clients

12.3 Disclaimer

Methodology/Research Approach

This research study involved the extensive usage of both primary and secondary data sources. The research process involved the study of various factors affecting the industry, including the government policy, market environment, competitive landscape, historical data, present trends in the market, technological innovation, upcoming technologies and the technical progress in related industry, and market risks, opportunities, market barriers and challenges. The following illustrative figure shows the market research methodology applied in this report.

Research Programs/Design

Historical Data (2015-2019)	Industry Trends Competitive Landscape By Company Expansion Mergers and Acquisitions Market Segment by Type by Application By Regions/ Geography	Value Status and Outlook Value for Major Players Market Share Growth Rate Present Situation Analysis Value Market Share Growth Rate Present Situation Analysis
Influencing Factors	Market Environment Government Policy Technological Changes Market Risks	Market Drivers Growing Demand of Downstream Reduction in Cost
Market Forecast (2021-2026)	Overall Size by Type by Application By Regions/Geography	Key Data (Value) Market Share Growth Rate CAGR (2021-2026)

Market Size Estimation

Top-down and bottom-up approaches are used to validate the global Voluntary Carbon Offset market size market and estimate the market size for Company, regions segments, product segments and Application (end users).

The market estimations in this report are based on the marketed sale price of Voluntary Carbon Offset (excluding any discounts provided by the player, distributor, wholesaler or traders). The percentage splits, market share, and breakdowns of the product segments are derived on the basis of weights assigned to each of the segments on the basis of their utilization rate and average sale price. The regional splits of the overall Voluntary Carbon Offset market and its sub-segments are based on the percentage adoption or utilization of the given product in the respective region or country.

Major Company in the market is identified through secondary research and their market revenues determined through primary and secondary research. Secondary research included the research of the annual and financial reports of the top Company; whereas, primary research included extensive interviews of key opinion leaders and industry experts such as experienced front-line staff, directors, CEOs and marketing executives. The percentage splits, market share, Growth Rate and breakdowns of the product markets are determined through using secondary sources and verified through the primary sources.

All possible factors that influence the markets included in this research study have been accounted for, viewed in extensive detail, verified through primary research, and analyzed to get the final quantitative and qualitative data. The market size for top-level markets and sub-segments is normalized, and the effect of inflation, economic downturns, and regulatory & policy changes or other factors are not accounted for in the market forecast. This data is combined and added with detailed inputs and analysis from Market Intellix and presented in this report

The following figure shows an illustrative representation of the overall market size estimation process used for this study.

Market Breakdown and Data Triangulation

After complete market engineering with calculations for market statistics; market size estimations; market forecasting; market breakdown; and data triangulation, extensive primary research was conducted to gather information and verify and validate the critical numbers arrived at. In the complete market engineering process, both top-down and bottom-up approaches were extensively used, along with several data triangulation methods, to perform market estimation and market forecasting for the overall market segments and sub-segments listed in this report. Extensive qualitative and further quantitative analysis is also done from all the numbers arrived at in the complete market engineering process to list key information throughout the report.

Data Source

Secondary Sources

Secondary sources include such as press releases, annual reports, non-profit organizations, industry associations, governmental agencies and customs data, etc. This research study involves the usage of widespread secondary sources, directories, databases such as Bloomberg Business, Wind Info, Hoovers, Factiva (Dow Jones & Company), and TRADING ECONOMICS, and News Network, statista, Federal Reserve Economic Data, annual reports, BIS Statistics, ICIS; company house documents; CAS(American Chemical Society); investor presentations; and SEC filings of companies. Secondary research was used to identify and collect information useful for the extensive, technical, market-oriented, and Hospitals study of the Voluntary Carbon Offset market. It was also used to obtain important information about the top companies, market classification and segmentation according to industry trends to the bottom-most level, and key developments related to market and technology perspectives.

Market Size	Segmental value Geographic Penetration Product Adoption Rate for Different market	Journals, Websites, and Press Releases Annual Reports and SEC Filings Company Websites and Press Releases Public and Paid Databases Market Intellix Data Repository
Market Position of Top Company	Product Financials Geographic value Mix Total Company value Business/Segmental value Mix
Qualitative Analysis	Influence Factors Market Potential Market Risks and Opportunities Industry Trends Geographical Features Government Policies	Company Websites and Press Releases Public and Paid Databases Annual Reports Industry Associations Market Intellix Data Repository

Primary Sources

In the primary research process, various sources from both the supply and demand sides were interviewed to obtain qualitative and quantitative information for this report. The primary sources from the supply side include product Company (and their competitors), opinion leaders, industry experts, research institutions, distributors, dealer and traders, as well as the raw materials suppliers and producers, etc.

The primary sources from the demand side include industry experts such as business leaders, marketing and sales directors, technology and innovation directors, supply chain executive, end use (product buyers), and related key executives from various key companies and organizations operating in the global market.

Primary research was conducted to identify segmentation Type, product price range, product Application, key Company, raw materials supply and the downstream demand, industry status and outlook, and key market dynamics such as risks, influence factors, opportunities, market barriers, industry trends, and key player strategies.

Key Executives Interviewed

Key Data Information from Primary Sources

Primary Sources	Parameters	Key Data
Market Segments(by Application, by Type)	Value by Type Status and Forecast Value by Application Value by Regions, Status and Forecast (2021-2026)	Value Market Share by Type Value Growth Rate by Type Value by Application Percentage and Growth Rate by Application Value Growth Rate and Market Share by Regions Market Size Status and Forecast (2021-2026)
Total Market	Overall Size, Status and Forecast	Market Size Status and Forecast (2021-2026)