Europe small molecule API market was valued at $43.5 billion in 2022 and will grow by 7.4% annually over 2022-2032, driven by the increasing incidences of diseases, the development of high-potency small molecule APIs, patents expiry of the top-selling pharmaceuticals, the increasing technological developments in manufacturing sector, and a surging healthcare expenditure.

Highlighted with 70 tables and 52 figures, this 132-page report “Europe Small Molecule API Market 2022-2032 by Source (Synthetic, Semi-synthetic, Natural), Product Type (Standard, HPAPI), Therapeutic Area, Application (Clinical, Commercial), Manufacturer Type (Pharma, CMO), and Country: Trend Forecast and Growth Opportunity” is based on comprehensive research of the entire Europe small molecule API market and all its sub-segments through extensively detailed classifications. Profound analysis and assessment are generated from premium primary and secondary information sources with inputs derived from industry professionals across the value chain. The report is based on studies on 2020-2022 and provides forecast from 2023 till 2032 with 2022 as the base year. (Please note: The report will be updated before delivery so that the latest historical year is the base year, and the forecast covers at least 5 years over the base year.)

In-depth qualitative analyses include identification and investigation of the following aspects:

• Market Structure

• Growth Drivers

• Restraints and Challenges

• Emerging Product Trends & Market Opportunities

• Porter’s Fiver Forces

The trend and outlook of Europe market is forecast in optimistic, balanced, and conservative view by taking into account of COVID-19 and Russia-Ukraine conflict. The balanced (most likely) projection is used to quantify Europe small molecule API market in every aspect of the classification from perspectives of Source, Product Type, Therapeutic Area, Application, Manufacturer Type, and Country.

Based on Source, the Europe market is segmented into the following sub-markets with annual revenue ($ mn) for 2022-2032 included in each section.

• Synthetic API

o Branded Synthetic API

o Generic Synthetic API

• Semi-synthetic API

• Natural Origin

Based on Product Type, the Europe market is segmented into the following sub-markets with annual revenue ($ mn) for 2022-2032 included in each section.

• Standard API

• High Potency API (HPAPI)

o Branded HPAPI

o Generic HPAPI

By Therapeutic Area, the Europe market is segmented into the following sub-markets with annual revenue ($ mn) for 2022-2032 included in each section.

• Infectious Diseases

• Oncology

• Ophthalmology

• Cardiovascular Disorders

• Central Nervous System

• Respiratory Disorders

• Metabolic Diseases

• Other Therapeutic Areas

By Application, the Europe market is segmented into the following sub-markets with annual revenue ($ mn) for 2022-2032 included in each section.

• Clinical Use

• Commercial Use

By Manufacturer Type, the Europe market is segmented into the following sub-markets with annual revenue ($ mn) for 2022-2032 included in each section.

• Pharmaceutical Companies

• CMOs

Geographically, the following national/local markets are fully investigated:

• Germany

• UK

• France

• Spain

• Italy

• Russia

• Rest of Europe (further segmented into Netherlands, Switzerland, Poland, Sweden, Belgium, Austria, Ireland, Norway, Denmark, and Finland)

For each key country, detailed analysis and annual revenue ($ mn) are available for 2022-2032. The breakdown of national markets by Product Type, Therapeutic Area, and Manufacturer Type over the forecast years are also included.

The report also covers the current competitive scenario and the predicted trend; and profiles key vendors including market leaders and important emerging players.

Selected Key Players:

Aurobindo Pharma Ltd.

Cambrex Corporation

Catalent Inc.

Dr. Reddy's Laboratories

GlaxoSmithKline plc

Lonza Group

Merck & Co., Inc.

Mylan N.V.

Novartis AG

Pfizer Inc.

Sun Pharmaceutical Industries Ltd.

Teva Pharmaceutical Industries Ltd.

Wuxi AppTec Co., Ltd.

(Please note: The report will be updated before delivery so that the latest historical year is the base year, and the forecast covers at least 5 years over the base year.)

1 Introduction 8

1.1 Industry Definition and Research Scope 8

1.1.1 Industry Definition 8

1.1.2 Research Scope 9

1.2 Research Methodology 12

1.2.1 Overview of Market Research Methodology 12

1.2.2 Market Assumption 13

1.2.3 Secondary Data 13

1.2.4 Primary Data 13

1.2.5 Data Filtration and Model Design 14

1.2.6 Market Size/Share Estimation 15

1.2.7 Research Limitations 16

1.3 Executive Summary 17

2 Market Overview and Dynamics 20

2.1 Market Size and Forecast 20

2.1.1 Impact of COVID-19 on World Economy 21

2.1.2 Impact of COVID-19 on the Market 24

2.1.3 Impact of Russia-Ukraine Conflict: War Slows Economic Recovery 26

2.2 Major Growth Drivers 30

2.3 Market Restraints and Challenges 34

2.4 Emerging Opportunities and Market Trends 37

2.5 Porter’s Fiver Forces Analysis 41

3 Segmentation of Europe Market by Source 45

3.1 Market Overview by Source 45

3.2 Synthetic API 47

3.2.1 Branded Synthetic API 48

3.2.2 Generic Synthetic API 49

3.3 Semi-synthetic API 50

3.4 Natural Origin 51

4 Segmentation of Europe Market by Product Type 52

4.1 Market Overview by Product Type 52

4.2 Standard API 54

4.3 High Potency API (HPAPI) 55

4.3.1 Branded HPAPI 56

4.3.2 Generic HPAPI 57

5 Segmentation of Europe Market by Therapeutic Area 58

5.1 Market Overview by Therapeutic Area 58

5.2 Infectious Diseases 60

5.3 Oncology 61

5.4 Ophthalmology 62

5.5 Cardiovascular Disorders 63

5.6 Central Nervous System 64

5.7 Respiratory Disorders 65

5.8 Metabolic Diseases 66

5.9 Other Therapeutic Areas 67

6 Segmentation of Europe Market by Application 68

6.1 Market Overview by Application 68

6.2 Clinical Use 70

6.3 Commercial Use 71

7 Segmentation of Europe Market by Manufacturer Type 72

7.1 Market Overview by Manufacturer Type 72

7.2 Pharmaceutical Companies 74

7.3 CMOs 76

8 European Market 2022-2032 by Country 78

8.1 Overview of European Market 78

8.2 Germany 81

8.3 U.K. 83

8.4 France 85

8.5 Spain 87

8.6 Italy 89

8.7 Russia 91

8.8 Rest of European Market 93

9 Competitive Landscape 95

9.1 Overview of Key Vendors 95

9.2 New Product Launch, Partnership, Investment, and M&A 98

9.3 Company Profiles 99

Aurobindo Pharma Ltd. 99

Cambrex Corporation 101

Catalent Inc. 102

Dr. Reddy's Laboratories 105

GlaxoSmithKline plc 108

Lonza Group 112

Merck & Co., Inc. 115

Mylan N.V. 117

Novartis AG 119

Pfizer Inc. 121

Sun Pharmaceutical Industries Ltd. 125

Teva Pharmaceutical Industries Ltd. 128

Wuxi AppTec Co., Ltd. 130

RELATED REPORTS 132

List of Tables:

Table 1. Snapshot of Europe Small Molecule API Market in Balanced Perspective, 2022-2032 18

Table 2. World Economic Outlook, 2021-2031 22

Table 3. World Economic Outlook, 2021-2023 23

Table 4. Scenarios for Economic Impact of Ukraine Crisis 27

Table 5. World Health Spending by Region, $ bn, 2013-2020 32

Table 6. World Top 10 Pharmaceutical Companies Based on Projected R&D Spending in 2026, $ bn 33

Table 7. Main Product Trends and Market Opportunities in Europe Small Molecule API Market 37

Table 8. Europe Small Molecule API Market by Source, 2022-2032, $ mn 45

Table 9. Europe Small Molecule API Market: Synthetic API by Drug Type, 2022-2032, $ mn 47

Table 10. Europe Small Molecule API Market by Product Type, 2022-2032, $ mn 52

Table 11. Europe Small Molecule API Market: HPAPI by Drug Type, 2022-2032, $ mn 55

Table 12. Europe Small Molecule API Market by Therapeutic Area, 2022-2032, $ mn 58

Table 13. Europe Small Molecule API Market by Application, 2022-2032, $ mn 68

Table 14. Europe Small Molecule API Market by Manufacturer Type, 2022-2032, $ mn 72

Table 15. Europe Small Molecule API Market by Country, 2022-2032, $ mn 80

Table 16. Germany Small Molecule API Market by Product Type, 2022-2032, $ mn 82

Table 17. Germany Small Molecule API Market by Therapeutic Area, 2022-2032, $ mn 82

Table 18. Germany Small Molecule API Market by Manufacturer Type, 2022-2032, $ mn 82

Table 19. U.K. Small Molecule API Market by Product Type, 2022-2032, $ mn 84

Table 20. U.K. Small Molecule API Market by Therapeutic Area, 2022-2032, $ mn 84

Table 21. U.K. Small Molecule API Market by Manufacturer Type, 2022-2032, $ mn 84

Table 22. France Small Molecule API Market by Product Type, 2022-2032, $ mn 86

Table 23. France Small Molecule API Market by Therapeutic Area, 2022-2032, $ mn 86

Table 24. France Small Molecule API Market by Manufacturer Type, 2022-2032, $ mn 86

Table 25. Spain Small Molecule API Market by Product Type, 2022-2032, $ mn 88

Table 26. Spain Small Molecule API Market by Therapeutic Area, 2022-2032, $ mn 88

Table 27. Spain Small Molecule API Market by Manufacturer Type, 2022-2032, $ mn 88

Table 28. Italy Small Molecule API Market by Product Type, 2022-2032, $ mn 90

Table 29. Italy Small Molecule API Market by Therapeutic Area, 2022-2032, $ mn 90

Table 30. Italy Small Molecule API Market by Manufacturer Type, 2022-2032, $ mn 90

Table 31. Russia Small Molecule API Market by Product Type, 2022-2032, $ mn 92

Table 32. Russia Small Molecule API Market by Therapeutic Area, 2022-2032, $ mn 92

Table 33. Russia Small Molecule API Market by Manufacturer Type, 2022-2032, $ mn 92

Table 34. Small Molecule API Market in Rest of Europe by Country, 2022-2032, $ mn 94

Table 35. Aurobindo Pharma Ltd.: Company Snapshot 99

Table 36. Aurobindo Pharma Ltd.: Business Segmentation 100

Table 37. Aurobindo Pharma Ltd.: Product Portfolio 100

Table 38. Cambrex Corporation: Company Snapshot 101

Table 39. Catalent Inc.: Company Snapshot 102

Table 40. Catalent Inc.: Business Segmentation in 2018 102

Table 41. Catalent Inc.: Product Portfolio 103

Table 42. Catalent Inc.: Revenue, 2018-2020, $ million 103

Table 43. Catalent Inc.: Revenue by Region in 2018 104

Table 44. Dr. Reddy's Laboratories: Company Snapshot 105

Table 45. Dr. Reddy's Laboratories: Business Segmentation 105

Table 46. Dr. Reddy's Laboratories: Revenue, 2018-2020, $ bn 106

Table 47. GlaxoSmithKline: Company Snapshot 108

Table 48. GlaxoSmithKline: Business Segmentation 109

Table 49. GlaxoSmithKline: Product Portfolio 110

Table 50. GlaxoSmithKline: Revenue, 2018-2020, $ bn 111

Table 51. Lonza Group: Company Snapshot 112

Table 52. Lonza Group: Business Segmentation in 2018 112

Table 53. Lonza Group: Product Portfolio 113

Table 54. Lonza Group: Revenue by Region in 2018 113

Table 55. Merck & Co., Inc.: Company Snapshot 115

Table 56. Merck & Co., Inc.: Business Segmentation 115

Table 57. Merck & Co., Inc.: Revenue, 2018-2020, $ bn 116

Table 58. Mylan NV: Company Snapshot 117

Table 59. Mylan NV: Revenue, 2017-2019, $ bn 118

Table 60. Novartis International AG: Company Snapshot 119

Table 61. Novartis International AG: Business Segmentation 119

Table 62. Novartis International AG: Revenue, 2017-2019, $ bn 120

Table 63. Pfizer Inc.: Company Snapshot 121

Table 64. Pfizer Inc.: Business Segmentation 122

Table 65. Pfizer Inc.: Product Portfolio 123

Table 66. Pfizer Inc.: Revenue, 2018-2020, $ bn 123

Table 67. Sun Pharmaceutical Industries Limited: Company Snapshot 125

Table 68. Teva Pharmaceutical Industries Ltd.: Company Snapshot 128

Table 69. Teva Pharmaceutical Industries Ltd.: Business Segmentation 129

Table 70. WuXi AppTec Inc.: Company Snapshot 130


List of Figures:

Figure 1. Research Method Flow Chart 12

Figure 2. Bottom-up Approach and Top-down Approach for Market Estimation 15

Figure 3. Europe Market Forecast in Optimistic, Conservative and Balanced Perspectives, 2022-2032 17

Figure 4. Europe Small Molecule API Market, 2022-2032, $ mn 20

Figure 5. Impact of COVID-19 on Business 24

Figure 6. Primary Drivers and Impact Factors of Europe Small Molecule API Market 30

Figure 7. Primary Restraints and Impact Factors of Europe Small Molecule API Market 34

Figure 8. Investment Opportunity Analysis 38

Figure 9. Porter’s Fiver Forces Analysis of Europe Small Molecule API Market 41

Figure 10. Breakdown of Europe Small Molecule API Market by Source, 2022-2032, % of Revenue 46

Figure 11. Europe Addressable Market Cap in 2023-2032 by Source, Value ($ mn) and Share (%) 46

Figure 12. Europe Small Molecule API Market by Source: Synthetic API, 2022-2032, $ mn 47

Figure 13. Europe Small Molecule API Market by Synthetic API: Branded Synthetic API, 2022-2032, $ mn 48

Figure 14. Europe Small Molecule API Market by Synthetic API: Generic Synthetic API, 2022-2032, $ mn 49

Figure 15. Europe Small Molecule API Market by Source: Semi-synthetic API, 2022-2032, $ mn 50

Figure 16. Europe Small Molecule API Market by Source: Natural Origin, 2022-2032, $ mn 51

Figure 17. Breakdown of Europe Small Molecule API Market by Product Type, 2022-2032, % of Sales Revenue 53

Figure 18. Europe Addressable Market Cap in 2023-2032 by Product Type, Value ($ mn) and Share (%) 53

Figure 19. Europe Small Molecule API Market by Product Type: Standard API, 2022-2032, $ mn 54

Figure 20. Europe Small Molecule API Market by Product Type: High Potency API (HPAPI), 2022-2032, $ mn 55

Figure 21. Europe Small Molecule API Market by HPAPI: Branded HPAPI, 2022-2032, $ mn 56

Figure 22. Europe Small Molecule API Market by HPAPI: Generic HPAPI, 2022-2032, $ mn 57

Figure 23. Breakdown of Europe Small Molecule API Market by Therapeutic Area, 2022-2032, % of Sales Revenue 59

Figure 24. Europe Addressable Market Cap in 2023-2032 by Therapeutic Area, Value ($ mn) and Share (%) 59

Figure 25. Europe Small Molecule API Market by Therapeutic Area: Infectious Diseases, 2022-2032, $ mn 60

Figure 26. Europe Small Molecule API Market by Therapeutic Area: Oncology, 2022-2032, $ mn 61

Figure 27. Europe Small Molecule API Market by Therapeutic Area: Ophthalmology, 2022-2032, $ mn 62

Figure 28. Europe Small Molecule API Market by Therapeutic Area: Cardiovascular Disorders, 2022-2032, $ mn 63

Figure 29. Europe Small Molecule API Market by Therapeutic Area: Central Nervous System, 2022-2032, $ mn 64

Figure 30. Europe Small Molecule API Market by Therapeutic Area: Respiratory Disorders, 2022-2032, $ mn 65

Figure 31. Europe Small Molecule API Market by Therapeutic Area: Metabolic Diseases, 2022-2032, $ mn 66

Figure 32. Europe Small Molecule API Market by Therapeutic Area: Other Therapeutic Areas, 2022-2032, $ mn 67

Figure 33. Breakdown of Europe Small Molecule API Market by Application, 2022-2032, % of Revenue 69

Figure 34. Europe Addressable Market Cap in 2023-2032 by Application, Value ($ mn) and Share (%) 69

Figure 35. Europe Small Molecule API Market by Application: Clinical Use, 2022-2032, $ mn 70

Figure 36. Europe Small Molecule API Market by Application: Commercial Use, 2022-2032, $ mn 71

Figure 37. Breakdown of Europe Small Molecule API Market by Manufacturer Type, 2022-2032, % of Revenue 73

Figure 38. Europe Addressable Market Cap in 2023-2032 by Manufacturer Type, Value ($ mn) and Share (%) 73

Figure 39. Europe Small Molecule API Market by Manufacturer Type: Pharmaceutical Companies, 2022-2032, $ mn 74

Figure 40. Breakdown of Europe Small Molecule API In-house Synthesis Market by Region, 2020-2027, % of Revenue 75

Figure 41. Europe Small Molecule API Market by Manufacturer Type: CMOs, 2022-2032, $ mn 76

Figure 42. Breakdown of Europe Small Molecule API Contract Synthesis Market by Region, 2020-2027, % of Revenue 77

Figure 43. Breakdown of European Small Molecule API Market by Country, 2022 and 2032, % of Revenue 79

Figure 44. Contribution to Europe 2023-2032 Cumulative Market by Country, Value ($ mn) and Share (%) 80

Figure 45. Small Molecule API Market in Germany, 2022-2032, $ mn 81

Figure 46. Small Molecule API Market in U.K., 2022-2032, $ mn 83

Figure 47. Small Molecule API Market in France, 2022-2032, $ mn 85

Figure 48. Small Molecule API Market in Spain, 2022-2032, $ mn 87

Figure 49. Small Molecule API Market in Italy, 2022-2032, $ mn 89

Figure 50. Small Molecule API Market in Russia, 2022-2032, $ mn 91

Figure 51. Small Molecule API Market in Rest of Europe, 2022-2032, $ mn 93

Figure 52. Growth Stage of Europe Small Molecule API Industry over the Forecast Period 95

Methodology/Research Approach

This research study involved the extensive usage of both primary and secondary data sources. The research process involved the study of various factors affecting the industry, including the government policy, market environment, competitive landscape, historical data, present trends in the market, technological innovation, upcoming technologies and the technical progress in related industry, and market risks, opportunities, market barriers and challenges. The following illustrative figure shows the market research methodology applied in this report.

Research Programs/Design

Historical Data (2015-2019)	Industry Trends Competitive Landscape By Company Expansion Mergers and Acquisitions Market Segment by Type by Application By Regions/ Geography	Value Status and Outlook Value for Major Players Market Share Growth Rate Present Situation Analysis Value Market Share Growth Rate Present Situation Analysis
Influencing Factors	Market Environment Government Policy Technological Changes Market Risks	Market Drivers Growing Demand of Downstream Reduction in Cost
Market Forecast (2021-2026)	Overall Size by Type by Application By Regions/Geography	Key Data (Value) Market Share Growth Rate CAGR (2021-2026)

Market Size Estimation

Top-down and bottom-up approaches are used to validate the global Voluntary Carbon Offset market size market and estimate the market size for Company, regions segments, product segments and Application (end users).

The market estimations in this report are based on the marketed sale price of Voluntary Carbon Offset (excluding any discounts provided by the player, distributor, wholesaler or traders). The percentage splits, market share, and breakdowns of the product segments are derived on the basis of weights assigned to each of the segments on the basis of their utilization rate and average sale price. The regional splits of the overall Voluntary Carbon Offset market and its sub-segments are based on the percentage adoption or utilization of the given product in the respective region or country.

Major Company in the market is identified through secondary research and their market revenues determined through primary and secondary research. Secondary research included the research of the annual and financial reports of the top Company; whereas, primary research included extensive interviews of key opinion leaders and industry experts such as experienced front-line staff, directors, CEOs and marketing executives. The percentage splits, market share, Growth Rate and breakdowns of the product markets are determined through using secondary sources and verified through the primary sources.

All possible factors that influence the markets included in this research study have been accounted for, viewed in extensive detail, verified through primary research, and analyzed to get the final quantitative and qualitative data. The market size for top-level markets and sub-segments is normalized, and the effect of inflation, economic downturns, and regulatory & policy changes or other factors are not accounted for in the market forecast. This data is combined and added with detailed inputs and analysis from Market Intellix and presented in this report

The following figure shows an illustrative representation of the overall market size estimation process used for this study.

Market Breakdown and Data Triangulation

After complete market engineering with calculations for market statistics; market size estimations; market forecasting; market breakdown; and data triangulation, extensive primary research was conducted to gather information and verify and validate the critical numbers arrived at. In the complete market engineering process, both top-down and bottom-up approaches were extensively used, along with several data triangulation methods, to perform market estimation and market forecasting for the overall market segments and sub-segments listed in this report. Extensive qualitative and further quantitative analysis is also done from all the numbers arrived at in the complete market engineering process to list key information throughout the report.

Data Source

Secondary Sources

Secondary sources include such as press releases, annual reports, non-profit organizations, industry associations, governmental agencies and customs data, etc. This research study involves the usage of widespread secondary sources, directories, databases such as Bloomberg Business, Wind Info, Hoovers, Factiva (Dow Jones & Company), and TRADING ECONOMICS, and News Network, statista, Federal Reserve Economic Data, annual reports, BIS Statistics, ICIS; company house documents; CAS(American Chemical Society); investor presentations; and SEC filings of companies. Secondary research was used to identify and collect information useful for the extensive, technical, market-oriented, and Hospitals study of the Voluntary Carbon Offset market. It was also used to obtain important information about the top companies, market classification and segmentation according to industry trends to the bottom-most level, and key developments related to market and technology perspectives.

Market Size	Segmental value Geographic Penetration Product Adoption Rate for Different market	Journals, Websites, and Press Releases Annual Reports and SEC Filings Company Websites and Press Releases Public and Paid Databases Market Intellix Data Repository
Market Position of Top Company	Product Financials Geographic value Mix Total Company value Business/Segmental value Mix
Qualitative Analysis	Influence Factors Market Potential Market Risks and Opportunities Industry Trends Geographical Features Government Policies	Company Websites and Press Releases Public and Paid Databases Annual Reports Industry Associations Market Intellix Data Repository

Primary Sources

In the primary research process, various sources from both the supply and demand sides were interviewed to obtain qualitative and quantitative information for this report. The primary sources from the supply side include product Company (and their competitors), opinion leaders, industry experts, research institutions, distributors, dealer and traders, as well as the raw materials suppliers and producers, etc.

The primary sources from the demand side include industry experts such as business leaders, marketing and sales directors, technology and innovation directors, supply chain executive, end use (product buyers), and related key executives from various key companies and organizations operating in the global market.

Primary research was conducted to identify segmentation Type, product price range, product Application, key Company, raw materials supply and the downstream demand, industry status and outlook, and key market dynamics such as risks, influence factors, opportunities, market barriers, industry trends, and key player strategies.

Key Executives Interviewed

Key Data Information from Primary Sources

Primary Sources	Parameters	Key Data
Market Segments(by Application, by Type)	Value by Type Status and Forecast Value by Application Value by Regions, Status and Forecast (2021-2026)	Value Market Share by Type Value Growth Rate by Type Value by Application Percentage and Growth Rate by Application Value Growth Rate and Market Share by Regions Market Size Status and Forecast (2021-2026)
Total Market	Overall Size, Status and Forecast	Market Size Status and Forecast (2021-2026)